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Energetic contribution of non-essential 5′ sequence to catalysis in a hepatitis delta virus ribozyme
Hepatitis delta virus (HDV) ribozymes employ multiple catalytic strategies to achieve overall rate enhancement of RNA cleavage. These strategies include general acid–base catalysis by a cytosine side chain and involvement of divalent metal ions. Here we used a trans-acting form of the antigenomic ri...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125606/ https://ncbi.nlm.nih.gov/pubmed/11532952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4884 |
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