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Energetic contribution of non-essential 5′ sequence to catalysis in a hepatitis delta virus ribozyme

Hepatitis delta virus (HDV) ribozymes employ multiple catalytic strategies to achieve overall rate enhancement of RNA cleavage. These strategies include general acid–base catalysis by a cytosine side chain and involvement of divalent metal ions. Here we used a trans-acting form of the antigenomic ri...

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Detalhes bibliográficos
Main Authors: Shih, I.-hung, Been, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125606/
https://ncbi.nlm.nih.gov/pubmed/11532952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.17.4884
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