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Non-ribozyme sequences enhance self-cleavage of ribozymes derived from Hepatitis delta virus.

Analysis of the self-cleavage of ribozymes derived from the genomic RNA of Hepatitis delta virus (HDV) has revealed that certain co-transcribed vector sequences significantly affect the activity of the ribozyme. Specifically, the t1/2 of self-cleavage for a 135 nucleotide HDV RNA varied, at 42 degre...

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Bibliografiska uppgifter
Huvudupphovsmän: Belinsky, M G, Dinter-Gottlieb, G
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC333648/
https://ncbi.nlm.nih.gov/pubmed/2011528
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