Non-ribozyme sequences enhance self-cleavage of ribozymes derived from Hepatitis delta virus.
Analysis of the self-cleavage of ribozymes derived from the genomic RNA of Hepatitis delta virus (HDV) has revealed that certain co-transcribed vector sequences significantly affect the activity of the ribozyme. Specifically, the t1/2 of self-cleavage for a 135 nucleotide HDV RNA varied, at 42 degre...
Gespeichert in:
| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1991
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333648/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2011528/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.3.559 |
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