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PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA
The promyelocytic leukemia protein PML is organized into nuclear bodies which mediate suppression of oncogenic transformation and of growth. The biochemical functions of PML bodies are unknown, despite their involvement in several human disorders. We demonstrate that eukaryotic initiation factor 4E...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125576/ https://ncbi.nlm.nih.gov/pubmed/11500381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.16.4547 |
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