Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1

Heat shock factor 1 (HSF1) is a serine-rich constitutively phosphorylated mediator of the stress response. Upon stress, HSF1 forms DNA-binding trimers, relocalizes to nuclear granules, undergoes inducible phosphorylation and acquires the properties of a transactivator. HSF1 is phosphorylated on mult...

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Detalhes bibliográficos
Main Authors: Holmberg, Carina I., Hietakangas, Ville, Mikhailov, Andrey, Rantanen, Jouni O., Kallio, Marko, Meinander, Annika, Hellman, Jukka, Morrice, Nick, MacKintosh, Carol, Morimoto, Richard I., Eriksson, John E., Sistonen, Lea
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125548/
https://ncbi.nlm.nih.gov/pubmed/11447121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.14.3800
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