Phosphorylation of Serine 303 Is a Prerequisite for the Stress-Inducible SUMO Modification of Heat Shock Factor 1

The heat shock response, which is accompanied by a rapid and robust upregulation of heat shock proteins (Hsps), is a highly conserved protection mechanism against protein-damaging stress. Hsp induction is mainly regulated at transcriptional level by stress-inducible heat shock factor 1 (HSF1). Upon...

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Detalhes bibliográficos
Main Authors: Hietakangas, Ville, Ahlskog, Johanna K., Jakobsson, Annika M., Hellesuo, Maria, Sahlberg, Niko M., Holmberg, Carina I., Mikhailov, Andrey, Palvimo, Jorma J., Pirkkala, Lila, Sistonen, Lea
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152542/
https://ncbi.nlm.nih.gov/pubmed/12665592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.8.2953-2968.2003
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