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Adenylyl cyclase Rv1625c of Mycobacterium tuberculosis: a progenitor of mammalian adenylyl cyclases
The gene Rv1625c from Mycobacterium tuberculosis encodes a membrane-anchored adenylyl cyclase corresponding to exactly one-half of a mammalian adenylyl cyclase. An engineered, soluble form of Rv1625c was expressed in Escherichia coli. It formed a homodimeric cyclase with two catalytic centers. Amino...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Oxford University Press
2001
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125536/ https://ncbi.nlm.nih.gov/pubmed/11447108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.14.3667 |
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