Adenylyl cyclase Rv1625c of Mycobacterium tuberculosis: a progenitor of mammalian adenylyl cyclases

The gene Rv1625c from Mycobacterium tuberculosis encodes a membrane-anchored adenylyl cyclase corresponding to exactly one-half of a mammalian adenylyl cyclase. An engineered, soluble form of Rv1625c was expressed in Escherichia coli. It formed a homodimeric cyclase with two catalytic centers. Amino...

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Pubblicato in:	EMBO J
Autori principali:	Guo, Ying Lan, Seebacher, Thomas, Kurz, Ursula, Linder, Jürgen U., Schultz, Joachim E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2001
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447108/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.14.3667
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