Cell-autonomous and non-cell-autonomous functions of the Rb tumor suppressor in developing central nervous system

The retinoblastoma tumor suppressor (RB) plays an important role in the regulation of cell cycle progression and terminal differentiation of many cell types. Rb(–/–) mouse embryos die at midgestation with defects in cell cycle regulation, control of apoptosis and terminal differentiation. However, c...

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Detalles Bibliográficos

Publicado en:	EMBO J
Autores principales:	Lipinski, Marta M., Macleod, Kay F., Williams, Bart O., Mullaney, Tara L., Crowley, Denise, Jacks, Tyler
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 2001
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11432828/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.13.3402
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