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Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation
Sec1p-like/Munc-18 (SM) proteins bind to t-SNAREs and inhibit ternary complex formation. Paradoxically, the absence of SM proteins does not result in constitutive membrane fusion. Here, we show that in yeast cells lacking the SM protein Vps45p, the t-SNARE Tlg2p is down-regulated, to undetectable le...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125511/ https://ncbi.nlm.nih.gov/pubmed/11432826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3380 |
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