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Vps45p stabilizes the syntaxin homologue Tlg2p and positively regulates SNARE complex formation

Sec1p-like/Munc-18 (SM) proteins bind to t-SNAREs and inhibit ternary complex formation. Paradoxically, the absence of SM proteins does not result in constitutive membrane fusion. Here, we show that in yeast cells lacking the SM protein Vps45p, the t-SNARE Tlg2p is down-regulated, to undetectable le...

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Detalles Bibliográficos
Main Authors: Bryant, Nia J., James, David E.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC125511/
https://ncbi.nlm.nih.gov/pubmed/11432826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.13.3380
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