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The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation

Fusion of intracellular trafficking vesicles is mediated by the assembly of SNARE proteins into membrane-bridging complexes. SNARE-mediated membrane fusion requires Sec1/Munc18-family (SM) proteins, SNARE chaperones that can function as templates to catalyze SNARE complex assembly. Paradoxically, th...

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Autors principals: Travis J Eisemann, Frederick Allen, Kelly Lau, Gregory R Shimamura, Philip D Jeffrey, Frederick M Hughson
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2020-08-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/60724
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