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Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1

Heme controls expression of genes involved in the synthesis of globins and heme. The mammalian transcription factor Bach1 functions as a repressor of the Maf recognition element (MARE) by forming antagonizing hetero-oligomers with the small Maf family proteins. We show here that heme binds specifica...

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Gepubliceerd in:EMBO J
Hoofdauteurs: Ogawa, Kazuhiro, Sun, Jiying, Taketani, Shigeru, Nakajima, Osamu, Nishitani, Chiaki, Sassa, Shigeru, Hayashi, Norio, Yamamoto, Masayuki, Shibahara, Shigeki, Fujita, Hiroyoshi, Igarashi, Kazuhiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2001
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Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125477/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11387216/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.11.2835
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