Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1

Heme controls expression of genes involved in the synthesis of globins and heme. The mammalian transcription factor Bach1 functions as a repressor of the Maf recognition element (MARE) by forming antagonizing hetero-oligomers with the small Maf family proteins. We show here that heme binds specifica...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Ogawa, Kazuhiro, Sun, Jiying, Taketani, Shigeru, Nakajima, Osamu, Nishitani, Chiaki, Sassa, Shigeru, Hayashi, Norio, Yamamoto, Masayuki, Shibahara, Shigeki, Fujita, Hiroyoshi, Igarashi, Kazuhiko
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11387216/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.11.2835
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