Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1

Heme controls expression of genes involved in the synthesis of globins and heme. The mammalian transcription factor Bach1 functions as a repressor of the Maf recognition element (MARE) by forming antagonizing hetero-oligomers with the small Maf family proteins. We show here that heme binds specifica...

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Main Authors: Ogawa, Kazuhiro, Sun, Jiying, Taketani, Shigeru, Nakajima, Osamu, Nishitani, Chiaki, Sassa, Shigeru, Hayashi, Norio, Yamamoto, Masayuki, Shibahara, Shigeki, Fujita, Hiroyoshi, Igarashi, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125477/
https://ncbi.nlm.nih.gov/pubmed/11387216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2835
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