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26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide
Protein degradation by proteasomes is the source of most antigenic peptides presented on MHC class I molecules. To determine whether proteasomes generate these peptides directly or longer precursors, we developed new methods to measure the efficiency with which 26S and 20S particles, during degradat...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125470/ https://ncbi.nlm.nih.gov/pubmed/11350924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.10.2357 |
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