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26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide

Protein degradation by proteasomes is the source of most antigenic peptides presented on MHC class I molecules. To determine whether proteasomes generate these peptides directly or longer precursors, we developed new methods to measure the efficiency with which 26S and 20S particles, during degradat...

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Detalles Bibliográficos
Autores principales: Cascio, Paolo, Hilton, Craig, Kisselev, Alexei F., Rock, Kenneth L., Goldberg, Alfred L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC125470/
https://ncbi.nlm.nih.gov/pubmed/11350924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.10.2357
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