SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome

SMNrp, also termed SPF30, has recently been identified in spliceosomes assembled in vitro. We have functionally characterized this protein and show that it is an essential splicing factor. We show that SMNrp is a 17S U2 snRNP-associated protein that appears in the pre-spliceosome (complex A) and the...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Meister, Gunter, Hannus, Stefan, Plöttner, Oliver, Baars, Tonie, Hartmann, Enno, Fakan, Stanislav, Laggerbauer, Bernhard, Fischer, Utz
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11331595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.9.2304
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