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Oligopeptide repeats in the yeast protein Sup35p stabilize intermolecular prion interactions
The nuclear-encoded Sup35p protein is responsible for the prion-like [PSI(+)] determinant of yeast, with Sup35p existing largely as a high molecular weight aggregate in [PSI(+)] strains. Here we show that the five oligopeptide repeats present at the N-terminus of Sup35p are responsible for stabilizi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125439/ https://ncbi.nlm.nih.gov/pubmed/11331577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.9.2111 |
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