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Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library

RNA interference (RNAi) is a powerful tool for identifying gene function in Trypanosoma brucei. We generated an RNAi library, the first of its kind in any organism, by ligation of genomic fragments into the vector pZJMβ. After transfection at ∼5-fold genome coverage, trypanosomes were induced to exp...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Morris, James C., Wang, Zefeng, Drew, Mark E., Englund, Paul T.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125414/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf474
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