Enhanced repair of cyclobutane pyrimidine dimers and improved UV resistance in photolyase transgenic mice

During evolution, placental mammals appear to have lost cyclobutane pyrimidine dimer (CPD) photolyase, an enzyme that efficiently removes UV-induced CPDs from DNA in a light-dependent manner. As a consequence, they have to rely solely on the more complex, and for this lesion less efficient, nucleoti...

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書誌詳細
主要な著者: Schul, Wouter, Jans, Judith, Rijksen, Yvonne M.A., Klemann, Kyra H.M., Eker, Andre P.M., de Wit, Jan, Nikaido, Osamu, Nakajima, Satoshi, Yasui, Akira, Hoeijmakers, Jan H.J., van der Horst, Gijsbertus T.J.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2002
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC125407/
https://ncbi.nlm.nih.gov/pubmed/12198174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf456
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