Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

The p53 tumor suppressor is inhibited and destabilized by Mdm2. However, under stress conditions, this downregulation is relieved, allowing the accumulation of biologically active p53. Recently we showed that c-Abl is important for p53 activation under stress conditions. In response to DNA damage, c...

詳細記述

書誌詳細

出版年:	EMBO J
主要な著者:	Goldberg, Zehavit, Vogt Sionov, Ronit, Berger, Michael, Zwang, Yaara, Perets, Ruth, Van Etten, Richard A., Oren, Moshe, Taya, Yoichi, Haupt, Ygal
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Publishing Group 2002
主題:	Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125401/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12110584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf384
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!