Spi-B can functionally replace PU.1 in myeloid but not lymphoid development
Mature macrophages, neutrophils and lymphoid cells do not develop in PU.1(–/–) mice. In contrast, mice lacking the highly related protein Spi-B generate all hematopoietic lineages but display a B-cell receptor signaling defect. These distinct phenotypes could result from functional differences betwe...
I tiakina i:
| I whakaputaina i: | EMBO J |
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| Ngā kaituhi matua: | , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Nature Publishing Group
2002
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125373/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11980719/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.9.2220 |
| Ngā Tūtohu: |
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