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GCAP1 rescues rod photoreceptor response in GCAP1/GCAP2 knockout mice
Visual transduction in retinal photoreceptors operates through a dynamic interplay of two second messengers, Ca(2+) and cGMP. Ca(2+) regulates the activity of guanylate cyclase (GC) and the synthesis of cGMP by acting on a GC-activating protein (GCAP). While this action is critical for rapid termina...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2002
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125366/ https://ncbi.nlm.nih.gov/pubmed/11927539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1545 |
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