Rescue of ATPa3-deficient murine malignant osteopetrosis by hematopoietic stem cell transplantation in utero

Autosomal recessive osteopetrosis (ARO) is a paradigm for genetic diseases that cause severe, often irreversible, defects before birth. In ARO, osteoclasts cannot remove mineralized cartilage, bone marrow is severely reduced, and bone cannot be remodeled for growth. More than 50% of the patients sho...

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Detalhes bibliográficos
Main Authors: Frattini, Annalisa, Blair, Harry C., Sacco, Maria Grazia, Cerisoli, Francesco, Faggioli, Francesca, Catò, Enrica Mira, Pangrazio, Alessandra, Musio, Antonio, Rucci, Francesca, Sobacchi, Cristina, Sharrow, Allison C., Kalla, Sara E., Bruzzone, Maria Grazia, Colombo, Roberto, Magli, Maria Cristina, Vezzoni, Paolo, Villa, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1253616/
https://ncbi.nlm.nih.gov/pubmed/16195375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507637102
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