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TNFα inhibits skeletal myogenesis through a PW1-dependent pathway by recruitment of caspase pathways
Cachexia is associated with poor prognosis in patients with chronic disease. Tumor necrosis factor-alpha (TNFα) plays a pivotal role in mediating cachexia and has been demonstrated to inhibit skeletal muscle differentiation in vitro. It has been proposed that TNFα-mediated activation of NFκB leads t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125350/ https://ncbi.nlm.nih.gov/pubmed/11847111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.4.631 |
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