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TNFα-induced macrophage death via caspase-dependent and independent pathways

Macrophages are the principal source of TNFα, yet they are highly resistant to TNFα-mediated cell death. Previously, employing in vitro differentiated human macrophages, we showed that following the inhibition of NF-κB, TNFα-induced caspase-8 activation contributes to DNA fragmentation but is not ne...

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Detalhes bibliográficos
Main Authors: Tran, Tri M., Temkin, Vladislav, Shi, Bo, Pagliari, Lisa, Daniel, Soizic, Ferran, Christiane, Pope, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692057/
https://ncbi.nlm.nih.gov/pubmed/19152111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-009-0311-4
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