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Muscle cachexia is regulated by a p53–PW1/Peg3-dependent pathway

Muscle wasting (cachexia) is an incurable complication associated with chronic infection and cancers that leads to an overall poor prognosis for recovery. Tumor necrosis factor-α (TNFα) is a key inflammatory cytokine associated with cachexia. TNFα inhibits myogenic differentiation and skeletal muscl...

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Detalhes bibliográficos
Main Authors: Schwarzkopf, Martina, Coletti, Dario, Sassoon, David, Marazzi, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698450/
https://ncbi.nlm.nih.gov/pubmed/17182869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.412606
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