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Muscle cachexia is regulated by a p53–PW1/Peg3-dependent pathway
Muscle wasting (cachexia) is an incurable complication associated with chronic infection and cancers that leads to an overall poor prognosis for recovery. Tumor necrosis factor-α (TNFα) is a key inflammatory cytokine associated with cachexia. TNFα inhibits myogenic differentiation and skeletal muscl...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698450/ https://ncbi.nlm.nih.gov/pubmed/17182869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.412606 |
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