β-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2
G-protein-coupled receptor kinase 2 (GRK2) plays a key role in the regulation of G-protein-coupled receptors (GPCRs). GRK2 expression is altered in several pathological conditions, but the molecular mechanisms that modulate GRK2 cellular levels are largely unknown. We recently have described that GR...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11566877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.18.5129 |
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