β-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2

G-protein-coupled receptor kinase 2 (GRK2) plays a key role in the regulation of G-protein-coupled receptors (GPCRs). GRK2 expression is altered in several pathological conditions, but the molecular mechanisms that modulate GRK2 cellular levels are largely unknown. We recently have described that GR...

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Publié dans:	EMBO J
Auteurs principaux:	Penela, Petronila, Elorza, Ana, Sarnago, Susana, Mayor, Federico
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125273/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11566877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.18.5129
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