Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the ε-subunit and their functions in vivo

Eukaryotic initiation factor (eIF) 2B is a heteromeric guanine nucleotide exchange factor that plays an important role in regulating mRNA translation. Here we identify multiple phosphorylation sites in the largest, catalytic, subunit (ε) of mammalian eIF2B. These sites are phosphorylated by four dif...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Wang, Xuemin, Paulin, Fiona E.M., Campbell, Linda E., Gomez, Edith, O’Brien, Kirsty, Morrice, Nicholas, Proud, Christopher G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500362/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4349
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