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Mechanism of translational control by partial phosphorylation of the alpha subunit of eukaryotic initiation factor 2.

Catalysis of ternary complex formation by the GDP exchange factor (GEF), in the presence of Mg2+, is blocked by phosphorylation of the alpha subunit of the eukaryotic initiation factor 2 (eIF-2). We proposed earlier that this phosphorylation interferes with the interaction between eIF-2 and GEF (the...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Siekierka, J, Manne, V, Ochoa, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1984
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6320181/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.2.352
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