Mechanism of translational control by partial phosphorylation of the alpha subunit of eukaryotic initiation factor 2.

Catalysis of ternary complex formation by the GDP exchange factor (GEF), in the presence of Mg2+, is blocked by phosphorylation of the alpha subunit of the eukaryotic initiation factor 2 (eIF-2). We proposed earlier that this phosphorylation interferes with the interaction between eIF-2 and GEF (the...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Siekierka, J, Manne, V, Ochoa, S
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1984
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6320181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.2.352
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