Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the ε-subunit and their functions in vivo

Eukaryotic initiation factor (eIF) 2B is a heteromeric guanine nucleotide exchange factor that plays an important role in regulating mRNA translation. Here we identify multiple phosphorylation sites in the largest, catalytic, subunit (ε) of mammalian eIF2B. These sites are phosphorylated by four dif...

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Publicado en:	EMBO J
Autores principales:	Wang, Xuemin, Paulin, Fiona E.M., Campbell, Linda E., Gomez, Edith, O’Brien, Kirsty, Morrice, Nicholas, Proud, Christopher G.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 2001
Materias:	Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125262/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11500362/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.16.4349
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