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Plasticity and adaptation of Ca(2+) signaling and Ca(2+)-dependent exocytosis in SERCA2(+/–) mice

Darier’s disease (DD) is a high penetrance, autosomal dominant mutation in the ATP2A2 gene, which encodes the SERCA2 Ca(2+) pump. Here we have used a mouse model of DD, a SERCA2(+/–) mouse, to define the adaptation of Ca(2+) signaling and Ca(2+)-dependent exocytosis to a deletion of one copy of the...

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Autors principals: Zhao, Xiao-Song, Shin, Dong Min, Liu, Lynne H., Shull, Gary E., Muallem, Shmuel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125253/
https://ncbi.nlm.nih.gov/pubmed/11387203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2680
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