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Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1
The trimeric Cdk7–cyclin H–Mat1 complex comprises the kinase subunit of basal transcription factor TFIIH and has been shown to function as a cyclin-dependent kinase (Cdk)-activating kinase. Herein we report that disruption of the murine Mat1 gene leads to peri-implantation lethality coincident with...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125252/ https://ncbi.nlm.nih.gov/pubmed/11387217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2844 |
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