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The active sites of the influenza cap-dependent endonuclease are on different polymerase subunits

The cap-dependent endonuclease of the influenza viral RNA polymerase, which produces the capped RNA primers that initiate viral mRNA synthesis, is comprised of two active sites, one for cap binding and one for endonuclease cleavage.We identify the amino acid sequences that constitute these two activ...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Li, Mei-Ling, Rao, Ping, Krug, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125234/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.8.2078
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