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Increase of Microcirculatory Blood Flow Enhances Penetration of Ciprofloxacin into Soft Tissue

The present study addressed the effect of microcirculatory blood flow on the ability of ciprofloxacin to penetrate soft tissues. Twelve healthy male volunteers were enrolled in an analyst-blinded, clinical pharmacokinetic study. A single intravenous dose of 200 mg of ciprofloxacin was administered o...

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Main Authors: Joukhadar, Christian, Dehghanyar, Pejman, Traunmüller, Friederike, Sauermann, Robert, Mayer-Helm, Bernhard, Georgopoulos, Apostolos, Müller, Markus
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251507/
https://ncbi.nlm.nih.gov/pubmed/16189092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4149-4153.2005
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