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Increase of Microcirculatory Blood Flow Enhances Penetration of Ciprofloxacin into Soft Tissue

The present study addressed the effect of microcirculatory blood flow on the ability of ciprofloxacin to penetrate soft tissues. Twelve healthy male volunteers were enrolled in an analyst-blinded, clinical pharmacokinetic study. A single intravenous dose of 200 mg of ciprofloxacin was administered o...

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Main Authors: Joukhadar, Christian, Dehghanyar, Pejman, Traunmüller, Friederike, Sauermann, Robert, Mayer-Helm, Bernhard, Georgopoulos, Apostolos, Müller, Markus
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251507/
https://ncbi.nlm.nih.gov/pubmed/16189092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4149-4153.2005
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