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Increase of Microcirculatory Blood Flow Enhances Penetration of Ciprofloxacin into Soft Tissue

The present study addressed the effect of microcirculatory blood flow on the ability of ciprofloxacin to penetrate soft tissues. Twelve healthy male volunteers were enrolled in an analyst-blinded, clinical pharmacokinetic study. A single intravenous dose of 200 mg of ciprofloxacin was administered o...

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Détails bibliographiques
Auteurs principaux: Joukhadar, Christian, Dehghanyar, Pejman, Traunmüller, Friederike, Sauermann, Robert, Mayer-Helm, Bernhard, Georgopoulos, Apostolos, Müller, Markus
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1251507/
https://ncbi.nlm.nih.gov/pubmed/16189092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.10.4149-4153.2005
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