High diversity and rapid changeover of expressed var genes during the acute phase of Plasmodium falciparum infections in human volunteers

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) proteins expressed on the surface of P. falciparum-infected erythrocytes undergo antigenic variation by switching the gene expressed within a repertoire of approximately 50 var genes per haploid genome. The switching of PfEMP1 plays an im...

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Bibliographic Details
Main Authors: Peters, Jennifer, Fowler, Elizabeth, Gatton, Michelle, Chen, Nanhua, Saul, Allan, Cheng, Qin
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC125014/
https://ncbi.nlm.nih.gov/pubmed/12142467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162349899
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