Mutations in Cytochrome b Resulting in Atovaquone Resistance Are Associated with Loss of Fitness in Plasmodium falciparum

Drug resistance in malarial parasites has become a major obstacle in the control of the disease. Strategies are urgently needed to control the development of resistance and to possibly reverse existing resistance. One key element required to reverse malaria drug resistance is for the parasites to “p...

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Detalhes bibliográficos
Main Authors: Peters, Jennifer M., Chen, Nanhua, Gatton, Michelle, Korsinczky, Michael, Fowler, Elizabeth V., Manzetti, Sergio, Saul, Allan, Cheng, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127342/
https://ncbi.nlm.nih.gov/pubmed/12121915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2435-2441.2002
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