Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages

Imprinting is an epigenetic modification leading to monoallelic expression of some genes, and disrupted imprinting is believed to be a barrier to human stem cell transplantation, based on studies that suggest that epigenetic marks are unstable in mouse embryonic germ (EG) and embryonic stem (ES) cel...

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Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Onyango, Patrick, Jiang, Shan, Uejima, Hiroshi, Shamblott, Michael J., Gearhart, John D., Cui, Hengmi, Feinberg, Andrew P.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124986/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12114541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.152327599
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