Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages

Imprinting is an epigenetic modification leading to monoallelic expression of some genes, and disrupted imprinting is believed to be a barrier to human stem cell transplantation, based on studies that suggest that epigenetic marks are unstable in mouse embryonic germ (EG) and embryonic stem (ES) cel...

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Detalhes bibliográficos
Main Authors: Onyango, Patrick, Jiang, Shan, Uejima, Hiroshi, Shamblott, Michael J., Gearhart, John D., Cui, Hengmi, Feinberg, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124986/
https://ncbi.nlm.nih.gov/pubmed/12114541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152327599
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