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Allele-Specific PCR Method Based on pncA and oxyR Sequences for Distinguishing Mycobacterium bovis from Mycobacterium tuberculosis: Intraspecific M. bovis pncA Sequence Polymorphism

An allele-specific amplification method based on two genetic polymorphisms to differentiate Mycobacterium tuberculosis from Mycobacterium bovis was tested. Based on the differences found at position 169 in the pncA genes from M. tuberculosis and M. bovis, a PCR system which was able to differentiate...

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Bibliographic Details
Published in:J Clin Microbiol
Main Authors: de los Monteros, Luz Elena Espinosa, Galán, Juan Carlos, Gutiérrez, Montserrat, Samper, Sofía, García Marín, Juan F., Martín, Carlos, Domínguez, Lucas, de Rafael, Luis, Baquero, Fernando, Gómez-Mampaso, Enrique, Blázquez, Jesús
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124842/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9431955/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jcm.36.1.239-242.1998
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