Mutations in the tat Gene Are Responsible for Human Immunodeficiency Virus Type 1 Postintegration Latency in the U1 Cell Line

Previous reports have demonstrated that the U1 cell line, a model for postintegration latency, is defective at the level of Tat function and can be rescued by exogenously provided Tat protein. Sequence analysis of tat cDNAs from the U1 cell line identified two distinct forms of Tat, in agreement wit...

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Bibliographic Details
Main Authors: Emiliani, Stephane, Fischle, Wolfgang, Ott, Melanie, Van Lint, Carine, Amella, Carol Ann, Verdin, Eric
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Animal Viruses
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC124653/
https://ncbi.nlm.nih.gov/pubmed/9445075
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