Immunization of Pigs with a Particle-Mediated DNA Vaccine to Influenza A Virus Protects against Challenge with Homologous Virus

Particle-mediated delivery of a DNA expression vector encoding the hemagglutinin (HA) of an H1N1 influenza virus (A/Swine/Indiana/1726/88) to porcine epidermis elicits a humoral immune response and accelerates the clearance of virus in pigs following a homotypic challenge. Mucosal administration of...

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Autores principales: Macklin, Michael D., McCabe, Dennis, McGregor, Martha W., Neumann, Veronica, Meyer, Todd, Callan, Robert, Hinshaw, Virginia S., Swain, William F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Viral Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC124630/
https://ncbi.nlm.nih.gov/pubmed/9445052
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