Coadministration of DNA Encoding Interleukin-6 and Hemagglutinin Confers Protection from Influenza Virus Challenge in Mice

This study was conducted to investigate whether Accell gene gun coadministration of DNA encoding human interleukin-6 (IL-6) would enhance protective immune responses in mice to an equine influenza A virus hemagglutinin (HA) DNA vaccine. Mice that received HA DNA alone exhibited accelerated clearance...

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Main Authors: Larsen, Diane L., Dybdahl-Sissoko, Naomi, McGregor, Martha W., Drape, Robert, Neumann, Veronica, Swain, William F., Lunn, D. Paul, Olsen, Christopher W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Viral Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC124660/
https://ncbi.nlm.nih.gov/pubmed/9445082
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