Coadministration of DNA Encoding Interleukin-6 and Hemagglutinin Confers Protection from Influenza Virus Challenge in Mice

This study was conducted to investigate whether Accell gene gun coadministration of DNA encoding human interleukin-6 (IL-6) would enhance protective immune responses in mice to an equine influenza A virus hemagglutinin (HA) DNA vaccine. Mice that received HA DNA alone exhibited accelerated clearance...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Virol
Hauptverfasser:	Larsen, Diane L., Dybdahl-Sissoko, Naomi, McGregor, Martha W., Drape, Robert, Neumann, Veronica, Swain, William F., Lunn, D. Paul, Olsen, Christopher W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Viral Pathogenesis and Immunity
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC124660/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9445082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.2.1704-1708.1998
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